Organ compatibility between donors and recipients is an important factor in ensuring successful organ transplantation. Donor-recipient matching involves a comprehensive evaluation process to mitigate the risk of organ rejection and increase the chances of long-term graft survival. This World Organ Donation Day, observed every year on August 13, experts tell us all the factors that need to be considered for a successful match.

Why is compatibility mandatory?

Compatibility involves assessing several factors to minimise the risk of rejection and maximise the chances of a successful transplant, said Dr Sanjay Yadav, consultant, liver transplant and HPB surgery, Narayana Superspeciality Hospital, Gurugram.

What is to be considered?

According to Dr Yadav, the matching process begins by evaluating the compatibility of blood type and tissue antigens between donors and recipients. “ABO blood group compatibility is a fundamental criterion, as mismatched blood types can lead to rapid rejection of the transplanted organ,” said Dr Yadav.